Efficacy of deferasirox for the treatment of iron overload in a child affected by Juvenile Hemochromatosis
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چکیده
منابع مشابه
Efficacy of deferasirox for the treatment of iron overload in a child affected by Juvenile Hemochromatosis
We report the case of a 7 years old girl with Juvenile Hemochromatosis, due to homozygous mutation of HJV, which had increased serum iron indices and liver iron overload in the absence of any clinical sign of disease. Oral iron chelation with low dose deferasirox showed good efficacy and no side effects. The oral iron chelator deferasirox could be a valid option for removing excess iron in earl...
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15 صفحه اولJuvenile hemochromatosis: HAMP mutation and severe iron overload treated with phlebotomies and deferasirox
Juvenile hemochromatosis (JH) is a rare condition classified as an autosomal recessive disorder that leads to severe iron absorption. JH usually affects people under the age of 30 and presents symptoms such as chronic liver damage, hypogonadotropic hypogonadism, cardiac diseases and endocrine dysfunctions. The present case reports a 29-year-old Brazilian woman with JH condition due to HAMP muta...
متن کاملA Phase 1/2, Dose-Escalation Trial of Deferasirox for the Treatment of Iron Overload in HFE-Related Hereditary Hemochromatosis
UNLABELLED Hereditary hemochromatosis (HH) is characterized by increased intestinal iron absorption that may result in iron overload. Although phlebotomy is widely practiced, it is poorly tolerated or contraindicated in patients with anemias, severe heart disease, or poor venous access, and compliance can vary. The once-daily, oral iron chelator, deferasirox (Exjade) may provide an alternative ...
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ژورنال
عنوان ژورنال: Case Reports in Clinical Medicine
سال: 2013
ISSN: 2325-7075,2325-7083
DOI: 10.4236/crcm.2013.22033